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早产儿胃电节律和胃食管反流的初步观察 |
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postpradially with Digitraper EGG (CTD,Sweden), placing the surface electrodes in upper abdomen according to projection of gastric antrum according to abdominal plane X-ray film. Esophageal 24 h pH monitoring was performed with Digitraper MK (CTD, Sweden) and the infants who were found to have infinite GER (with the percentage of reflux time more than 13% according to ESPGAN score) were treated with cisapride (0.2ml/kg, 3 times a day) for 10 days. EGG and 24 h pH test were repeated after the 10-day treatment. Results (1) GER was found in 21/41(51 %) cases. GER disappeared in 19/21 (91%) cases after treatment. (2) In the whole series of infants, during fasting and after feeding, bradygastria was found in (43.5±0.2)% and (47.7±3.9)%, normal rhythm in (33.2±2.9) % and (28.4±2.4)%, and tachygastria in (22.8±2.9)% and (22.5±2.5) %, respectively; the power ratio was 1.5±0.5. (3) The percentages of infants with and without GER who showed normal rhythm (2.4-3.7)cpm were (34±4)% and (32±4)% (P>0.05) before feeding and (29±3)% and (28±3) % (P>0.05) after feeding; the dominant frequencies were (2.4±0.4) cpm and (1.7±0.4) cpm (P<0.01) before feeding and (1.6±0.4) cpm,(1.8±0.3) cpm (P>0.05) postpradially; power ratio was 2.9±1.2 and 0.7±0.1 (P<0.01). (4) After treatment with cisapride, the percentage of normal rhythm, bradygastria, tachygastria and power ratio at fasting and after feeding had no significant difference, so was the dominant frequency. Conclusions (1) The distribution of gastric electric rhythm in premature infant (the frequencies of 2.4-3.7 cpm were seen in only about 30%) was different from that in adults. (2) The correlation between gastroelectric rhythm and GER in premature infants remains to be clarified. (3) cisapride could control gastric reflux of premature infants effectively, but could not alter the gastric rhythm during sh 上一页 [1] [2] [3] 下一页
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