中西医结合治疗糖尿病周围神经病变30例临床观察

【摘要】  　　目的 观察中西医结合疗法治疗糖尿病周围神经病(DPN)的临床疗效。方法 将60例DPN患者随机分为2组。对照组30例采用西医常规治疗，维生素B1 100 mg，维生素B12 500 μg，均每日1次肌肉注射。治疗组30例在对照组治疗基础上加服益气活血、化瘀通络中药治疗，每日1剂，水煎分2次温服。2组均1个月为1个疗程，2个疗程后统计疗效。结果 治疗组总有效率83.34%，对照组总有效率56.66%，2组比较差异有统计学意义（P<0.01）。结论 中西医合治疗糖尿病周围神经病疗效确切。

【关键词】  糖尿病神经病变 周围神经系统疾病 中西医结合疗法

　　Therapeutic effect of combination of TCM and western medical on diabetic peripheral neuropathy disease 

　　YAO Jianjing,  WANG Kangping, XU Liangzhou, et al.

　　Medical Department, Shijiazhuang Hospital of TCM, Hebei Province, Shijiazhuang  050051

　　【Abstract】  Objective To observe the therapeutic effect of TCM and western medical on diabetic peripheral neuropathy disease (DPND).Method  60 cases were treated at the section of outpatients were divided into two groups: control group with 30 cases and treatment group with 30 cases. Two groups were treated with western medical convention means, and the treatment group was remedied moreover with TCM.Result  The total effective rate in the treatment group is 83.34% while that of the control group is 56.66%. There is very significant difference between the two groups (P<0.01).Conclusion  Combination of TCM and western medical has certain effect on diabetic peripheral neuropathy.　
　
　　【Key words】  Diabetic neuropathy; Peripheral nervous system disease; Combination of TCM and Western medicine

　　 糖尿病周围神经病变（diabetic peripheral neurapathy，DPN）是糖尿病慢性并发症中最常见的一种，起病隐匿，进展缓慢，如不及时诊治，将会引起糖尿病足而引起截肢，从而增加病残率。2007-06—2008-02，我们应用中西医结合疗法治疗糖尿病周围神经病变30例，并与西医常规治疗30例对照观察，现报告如下。

　　1  资料与方法

　　1.1  诊断标准 

　　参照世界卫生组织(WHO)1999年糖尿病诊断及分类标准［1］，且具有以下条件：①患者自觉有肢体麻木、疼痛和(或)感觉异常；②四肢浅感觉减退或过敏；③腱反射减弱或消失；④排除其它原因的神经病变。

　　1.2  一般资料 

　　全部60例均为本院神经内科门诊患者，随机分为2组。治疗组30例，男14例，女16例；年龄29～76岁，平均(54.1±3.7)岁；均为２型糖尿病；糖尿病病程5～20年，平均(12±

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