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电针刺激视觉相关穴位光明穴的脑BOLDfMRI研究

point (GB37) stimulating and the second is sham acupoint stimulating. The BOLD-fMRI Images were required on a 1.5-T unit; For electroacupuncture, Device BT701-1A was used; The silver no-magnet acupuncture needles (Φ0.30 mm×25 mm) was used in our study. A block design as “RSRSRSRSRS” was adopted for the study. The fMRI Data were analyzed by using Statistical Parametric Mapping software implemented within Matlab. The datasets were normalized to a standard space within SPM2. For all studies, statistical thresholding at significance level of P<0.001 and k>20 was initially used to determine significant activation for each vexol.Results  ①Electroacupuncture stimulation of GB37 produced major hemodynamic signal change  in the superior, middle, inferior frontal gyrus (Broadmann 10,11,45,47); superior temporal gyrus (Broadmann 38); cuneus and lingual gyrus of occipital lobe (Broadmann 18,19).②Electroacupuncture stimulation of false acupoint produced major hemodynamic signal change in the superior, inferior parietal lobule (Broadmann 7, 40); superior, middle frontal gyrus (Broadmann 10,46);superior temporal gyrus (Broadmann 22);  limbic lobe,posterior cingulated (Broadmann 29).Conclusions  ①There is a special relationship between the acupoint related visual and the braincortices realated visual, and acupoints have their own attributes.②The cortical mechanisms of clinical effects induced by electroacupuncturing the acupoint related visual are related with accommodating the senior visual cortex.③The cortical mechanisms of electroacupuncturing true acupoint are not simple correspondence between acupoints and areas of brain visual cortex, and it should be a complex process mobilizing the more areas of brain cortices to take part in.
   
  【Key words】  BOLD-fMRI;Electroacupuncture;Acupoint;Guangming(GB37);Visual cortex

  针灸是中国传统医学的重要组成部分,针灸的疗效已被国内外医学界认可。但针灸的很多理论目前尚无法与现代科学接轨。因此,如何利用现代医学理论与技术研究说明针灸疗法,近年来已成为

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