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女性急性心肌梗塞的临床特点 |
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北京地区防治冠心病协作组
【摘要】 目的 为了解女性急性心肌梗塞(AMI)的临床特点，以提高防治效果。方法 对北京地区防治冠心病协作组1990～1991年连续收治的1 614例患者(男1 185，女429)，进行男女比较分析。根据患者年龄分为(<45，45～54，55～64，≥65岁)四组，比较患者例数、并发症及病死率。结果 四组男与女患者比例分别为17.8：1，6.1：1，3.2：1和1.8：1。女性并发心源性休克者明显多于男性。发病4周病死率，女性14.7％明显高于男性9.4％。在45～54岁组内，差异亦有显著性(1.2％比0.7％)。结论 提示与年龄有关的雌激素水平变化对女性AMI临床特点有明显的影响。
【关键词】 女性 心肌梗塞 雌激素
Clinical characteristics of acute myocardial infarction in female patients Beijing Collaborative Study Group of Coronary Heart Disease 100700 (correspondewce: Beijing General Hospital, PLA, Beijing 100700)
【Abstract】 Objective To investigate the clinical characteristics of female patients, with acute myocardial infarction(AMI). Methods One thousand, six hundred and fourteen patients of coronary heart disease (CHD) (male 1 185, female 429) admitted to 20 hospitals of Beijing Collaborative Study Group in 1991-1992 were analyzed to compare the clinical states of female with male patients. Patients were divided into 4 age groups (<45, 45-54, 55-64 and ≥65 years) to compare morbidity, complications and mortality rate. Results The ratios of female to male patients in the 4 groups were 17.8:1,6.1:1, 3.2:1 and 1.8:1, respectively. More female patients were complicated with cardiogenic shock. The 4-week post-infarction mortality rate in females (14.7%) was signific-antly higher than that of males(9.4%), which was also significantly different (1.2% vs 0.7%)in the 45-54 years group. Conclusion The results suggest that there is prominent influence of age-related estrogen on the AMI clinical course in female patients.
【Key words】 female myocardial infarction estrogen
本世纪初国外学者已有报道，冠心病(CHD)有明显性别差异。近年来,女性冠心病基础理论与临床防治的研究更引起广泛的重视，并有了很大的进展，为了解女性冠心病的临床特点，提高防治效果，对收治的AMI病例临床资料进行男女比较分析。
对象和方法
1.对象：1 614例患者为北京地区防治CHD协作组1990～1991年19所医院连续收治的病例，均按统一表格填写，休克、心力衰竭诊断标准、死亡原因分类进行登记［1］，并计算发病4周内病死率，AMI的诊断系根据病史、心电图及(或)血清酶学变化。
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