生长抑素联合云南白药治疗急性上消化道大出血

【摘要】  　　目的： 观察生长抑素联合云南白药治疗急性上消化道大出血的临床疗效。方法: 选择临床确诊的急性上消化道大出血患者156例，在常规药物治疗的基础上，持续静滴生长抑素（SS）或其类似物奥曲肽（Oct），同时间断口服或胃管内注入云南白药粉，按疗效判定标准判断治疗效果。结果: 156例患者中，显效77例（49.36%），平均止血时间为（20±4）h；有效65例（41.67%），平均止血时间为（38±10）h；无效14例（8.97%），总有效率为91.03%，14例无效患者中，9例转急诊手术或内镜治疗，4例死于失血性休克，1例死于大量呕血后窒息。结论: 生长抑素联合云南白药治疗急性上消化道大出血，疗效好，安全可靠。

【关键词】  生长抑素 云南白药 上消化道大出血

　　Somatostatin Combine Yunnan Baiyao Powder in Treating Acute Massive Bleeding from the Upper Alimentary Tract

　　JinYan-fen，Chen Fen，Tian Feng

　　Department of Gerontology，The First Affiliated Hospital of Kunming Medical College，Kunming 650032，China

　　【ABSTRACT】 Objective: To observe the curative effect with somatostatin combine yunnan baiyao powder in treating acute massive bleeding from the upper alimentary tract.  Methods:  Chose the clinical definite patient 156 cases for acute massive bleeding from the upper alimentary tract，with the basic drug treatment，keeping on droping the Somatostatin or its analog，meanwhile，take yunnan baiyao powder orally or abouchement into stomach tube，to judge the therapeutic efficacy according to the assessment standard for curative effect. Results:  In 156 cases，the curative effect of 77 patients (49.36%)is significant，average haemostasis time is (20±4)h; 65 patients is utility (41.67%)，average haemostasis time is (38±10)h; 14 patinets is ineffective(8.97%)，total effective rate is 91.03%. In the 14 ineffective patients，9 patients turn to the emergency operation or endoscope therapy，4 patients succumb to the hemorrhagic shock，1 patients succumb to the apnoea after the massive haematemesis.Conclusion:  Treating acute massive bleeding from the upper alimentary tract with Somatostatin combine yunnan baiyao powder，curative effect is good and reliability and safety.

　　【KEY WORDS】 Somatostatin; Yunnan baiyao powder; Massive hemorrhage of upper gastrointestinal tract

　　各种原因引起的急性上消化道大出血是内外科常见急症

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