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关于Notch1和Hes1 Hes5在星形细胞瘤中的表达及其相关性研究

oblastoma multiforme[J]. J Neurosurg,2007,106(3):417427.

  [5] Somasundaram K, Reddy S P, Vinnakota K, et al. Upregulation of ASCL1 and inhibition of Notch signaling pathway characterize progressive astrocytoma[J]. Oncogene, 2005,24(47):70737083.

  [6] Cheung H C, Corley L J, Fuller G N, et al. Polypyrimidine tract binding protein and Notch1 are independently reexpressed in glioma[J]. Mod Pathol, 2006,19(8):10341041.

  [7] Gray G E, Mann R S, Mitsiadis E, et al. Human ligands of the Notch receptor[J]. Am J Pathol, 1999,154(3):785794.

  [8] Zagouras P, Stifani S, Blaumueller C M, et al. Alterations in Notch signaling in neoplastic lesions of the human cervix[J]. Proc Natl Acad Sci U S A, 1995,92(14):64146418.

  [9] Miyamoto Y, Maitra A, Ghosh B, et al. Notch mediates TGF alphainduced changes in epithelial differentiation during pancreatic tumorigenesis[J]. Cancer Cell, 2003,3(6):565576.

  [10] Nickoloff B J, Osborne B A, Miele L. Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents[J]. Oncogene, 2003,22(42):65986608.

  [11] Kluppel M, Wrana J L. Turning it up a Notch: crosstalk between TGF beta and Notch signaling[J]. Bioessays, 2005,27(2):115118.

  [12] Gustafsson M V, Zheng X, Pereira T, et al. Hypoxia requires notch signaling to maintain the undifferentiated cell state[J]. Dev Cell, 2005,9(5):617628.

  [13] Diez H, Fischer A, Winkler A, et al. Hypoxiamediated activation of Dll4NotchHey2 signaling in endothelial progenitor cells andadoption of arterial cell fate[J]. Exp Cell Res, 2007,313(1):19.

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