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幽门螺杆菌工程疫苗研究进展

on of immunodominant antigens form Helicobacter pylori and evaluation of their reactivities with sera from patients with different gastroduodenal pathologies,Infect Immun.2000;68:915-920

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  [6]Dieterick C.Bouzourene H,Blum AL,Corthesy-Theulaz IE.Urease-based mucosal immunization against Helicobacter heilmannii infection induces corpus atrophy in mice.Infect Immun,1999;67:6206-6209

  [7]Ernst JD.Toward the development of antibacterial vaccines:report of a symposium and workshop.Organizing Committee.Clin Infect Dis,1999;29:1295-1302

  [8]Blanchard TG,Czinn SJ,Nedrud JG,Killeen KP,Hohmann EL.Host response and vaccine development to Helicobacter pylori infection.Curr Top Microbiol immunol,1999;241:181-213

  [9]Ghiara P,Rossi M,Marchetti M,Guidi L,Frasca D,Costanzo M.Therapeutic intragastric vaccination against Helicobacter Pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection.Infect immune,1997;65:4996-5002

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  [11]韩锋产,阎小君,苏成芝.幽门螺旋杆菌细胞毒素相关蛋白A及细胞空泡毒素A的研究,华人消化杂志,1998;6:160-161

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recombinant urease and LT adjuvant[abstract],Gastroenterology,1997;112:A1042

  [13]Kin SY,Doh HJ,Ahn JS,Tricerri D,Fuidi L,Induction of mucosal and systemic immune response by oral immunization with H,pylori lysates encapsulated in poly (D,L-lactide-co-glycolide)microparticles,Vaccine,1999;17:607-616

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