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静脉滴注赖氨匹林治疗小儿急性热病效果观察

陶春莲 裴桂英 朱国琼

  摘 要 目的: 探讨赖氨匹林(来比林)在小儿急性热病中的退热效果。 方法: 选择小儿急性发热性疾病体温>39 ℃者60例, 随机分组, 治疗组30例, 选用赖氨匹林静脉滴注对照组30例, 用安痛定肌肉注射, 分别在用药15和60 min后观测体温。 结果: 治疗组用药15 min后体温开始下降22例(73.3%), 对照组13例(40.0%), P<0.01; 治疗组用药60 min后体温降至正常28例(93.3%), 对照组27例(90%), P>0.05。 结论: 静脉滴注赖氨匹林用于小儿急性热性疾病退热, 起效明显快于安痛定组, 退热效果好, 无不良反应。
  关键词 赖氨匹林 热病, 急性/小儿 退热效果

Observation of Fever-Removing Effect of Intravenous Infusion of Lysinipinum on in Acute Juvenile Febrile Diseases

Tao Chunlian,Pei Guiying,Zhu Guoqiong
Department of Pediatrics, Wuhan Jungong General Hospital,Wuhan 430010,P.R.China

ABSTRACT To study the fever-removing effect of Lysinipinum on the acute juvenile febrile diseases ,60 children with acute febrile diseases,with temperature higher than 39 ℃ ,were studide.30 cases were given intravenous infusion of Lysiniqinum(trea tment group )and the other 30 patients were subjected to intramuscular injection of Antondin(control group).Temperature was observed 15 minutes and 30 minutes a fter the injection.The results showed that the temperature in treatment group be gan to fall 15 minutes after the treatment in 22 of the 30 cases (73.3%)whil e in the control group only 12 of the 30 cases(40%)began to drop 15 minutes afte the injection (P<0.01).60 minutes after the treatment ,the temperature in treatment group fell to normal in 28 of the 30 cases (93.3%)and in contr ol group, the temperature was reduced to the normal in 27 of 30 cases(90%,P> 0.05).The intravenous infusion of Lysinipinum was better than intramuscula r injection of Antondin in terms of fever-removing effect .Intravenous infusion of Lysinipinum also was also better than the intramuscular injection of Antondi n in that the former was safe and had less side effects.
  KEY WORDS Lysinipinum; Acute juvenile febrile diseases; Fever-removing effect

  发热是小儿急性感染性疾病常见症状, 常易引起高热惊厥, 临床上除了针对病因抗感染治疗外, 还必须及时作出有效地退热处理。 赖氨匹林作为一种安全的降温药, 不仅能静脉用药, 而且还可与大

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