传染性单核细胞增多症并肝损害的临床分析

传染性单核细胞增多症并肝损害的临床分析

　摘要：目的：分析儿童传染性单核细胞增多症（简称传单）并肝损害的临床特点。方法：回顾分析我院儿科2001年1月至2004年6月收治的传单并肝损害58例的临床资料。结果：58例患儿中有54例（93.1%）以血清乳酸脱氢酶、谷丙转氨酶、谷草转氨酶升高为主，4例重症病例除酶升高还合并胆红素升高、总蛋白及白蛋白降低。结论：传单并肝损害以转氨酶升高为主，部分可出现重症肝炎表现。

　　关键词:传染性单核细胞增多;肝损害

　　The Clinical Analysis of Infectious Mononucleosis  with Hepatic Lesion

　　WENG Chen-hua，LIN Ming-xiang，YANG Yu-fang

　　(Shantou  Central  Hospital,Guangdong Shantou 515031, China)

　　Abstract: Objective：The aim of the study was to analyse the clinical  characteristic  of  children `s infectious mononucleosis with hepatic lesion . Method：To retrospectively analyse  the clinical data of 58 children s infectious mononucleosis with hepatic lesion. Result: There were  54 cases（93.1%）whose  serum lactate dehydrogenase, glutamate-pyruvate transaminase and  glutamic oxalacetic transaminase were significant increased , and 4 cases whose bilirubin rose and total protein and albumin descreased. Conclusion: The main manifestation of infectious mononucleosis was increased aminopherase , and the manifestation of serious hepatitis could be seen in some children with infectious mononucleosis.

　　Key words:Infectious mononucleosis；Hepatic lesion
                                                             
　　传染性单核细胞增多症（简称传单）是由EB病毒引起的以侵犯淋巴系统为主的急性感染性疾病。临床上表现为发热、咽峡炎、肝脾和淋巴结肿大，外周血出现异形淋巴细胞，血清嗜异性反应阳性［1］。本病可累及全身多个系统，并发心、肝、肺、肾、胰腺、腮腺等器官损害。我院儿科自2001年1月至2004年6月收治的传单并肝损害58例，现报告如下：

　　1 临床资料

　　1.1 诊断标准：①全部病例均按张之南主编《血液学诊断及疗效标准》中关于传单的国内诊断标准［2］。②血清谷丙转氨酶升高超过40IU/L，伴或不伴肝脏肿大。③除外其它病毒肝炎。

　　1.2 一般资

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