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骨肽联合葡萄糖酸钙注射液治疗原发性骨质疏松症的疗效观察

【摘要】 目的 探讨骨肽联合葡萄糖酸钙治疗骨质疏松症的疗效。方法 原发性骨质疏松症患者56例,随机分为治疗组和对照组,各28例,在常规口服非甾体消炎镇痛药物及钙剂,适当补充维生素D治疗基础上,治疗组给予注射用骨肽50mg+0.9%氯化钠注射液250ml、10%葡萄糖酸钙注射液20ml+5%葡萄糖注射液250ml静滴,1次/日,(15~30)天为一疗程。结果 治疗组骨痛明显改善,腰椎及左侧股骨颈骨密度(BMD)均升高,对照组治疗前后骨密度(BMD)改变不明显。结论 骨肽联合葡萄糖酸钙注射液治疗骨质疏松症疗效确切。

  【关键词】 骨质疏松症 骨肽联合钙剂 治疗

  The therapeutic effect of combinating ossotide for injection with calcium gluconate injection on osteoporosis(HE Xiuhong,DING Qiongli. Department of Internal medicine,The 2nd people?蒺s hospital of Kunming,Yunnan 650204,China.)

  【Abstract】 Objective To explore the therapeutic effect of combinating ossatide for injection with calcium gluconate injection on osteoporosis(OP). Methods Total numbers(56 cases) suffering from OP were randomly divided into two groups,treatment group(28 cases) and the control group(28 cases). Each case in those two groups,based on the suitable replenished Vitamin D dose,was respectively treated with the same non-steroidal anti-inflammatory drugs(NSAIDS) and calcium tablets. Each case in treatment group was injected with Ossotide for injection(50mg) mixed sodium chloride injection(0.9%,250ml),calcium gluconate injection (10%,20ml) and glucose injection (5%,250ml) altogether once a day,which completely lasted 15~30 days as a whole period. Result The cases suffering from skeleton pains in treatment group have been effectively improved after treatment than those in control group. Not only the bonemassdensity(BMD) of the lumber vertebra but the bonemassdensity of the left thighbone neek has risen as well. In contrast,the control group haven?蒺t gottern any comfortable improvement compare to its pre-treatment. Conclusion The therapeutic effect of combinating ossotide for injection with calcium gluconate injection on osteoporosis is definite.

  【Key words】 osteoporosis,combination of ossotide with calcium gluconate for injection,treatment骨质疏松症是以骨量减少,骨微观结构退化、骨脆性增加,易引起腰背疼痛、骨痛甚至发生骨折的一种全身骨骼疾病。它严重威胁着老年人的身体健康,以往常用非甾体消炎镇痛药物治疗,多不能彻底解除疼痛

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