眩晕宁联合西比灵治疗椎

付跃波   吉大四院       神经内科    副主任医师  

【摘要】　目的　 比较眩晕宁联合西比灵与单用西比灵治疗椎-基底动脉供血不足引起眩晕的临床疗效。   方法　将100例椎-基底动脉供血不足患者随机均分成两组, 眩晕宁组服用西比灵( 10mg, 每日1次，每晚睡前服用) 加眩晕宁片(3片, 每日3 次)作为治疗组 , 疗程为60天, 最终完成50 例。西比灵组单服用西比灵( 10mg, 每日1次，每晚睡前服用)作为对照组，疗程为60天,最终完成50 例。结果　与对照组比较, 眩晕宁片治疗组治疗后能明显改善眩晕症状, 能使LVA, RVA, BA值升高, 对血液流变学各项指标也有较好改善, 2组间比较均有显著性差异( P < 0105) 。结论　眩晕宁片加用西比灵能显著提高椎基底动脉供血不足引起眩晕的疗效。
　　【关键词】　眩晕宁片; 西比灵; 椎-基底动脉供血不足; 眩晕
A Clinical Study of the Efficacy using Xuanyunning and Sibelium in Treatment of Vertigo Caused by Vertebrobasilar Insufficiency　
　　【Abstract】　Objective　To investigate the therapeutic efficacy of using Xuanyunning  with Sibelium in patients with vertebrobasilar insufficiency. Methods　100 patients with vertebrobasilar insufficiency were randomly divided into therapeutic group and control group. Fifty patients in the therapeutic group were given Xuanyunning 3 tablets tid and 10mg of Sibelium sid at night for 60 days, whereas the other 50 patients were treated routinely with Xuanyunning 3 tablets tid as the control group. p used traditional Chinesemedicine Xuanyunning. Pre - post treatment are significant with thanscranical colour doppler ( TCD) and clinical symptom. Results　Blood flow velocity and clinical symptom in pre - post treatment contrast are significantly different ( P < 0.05). Conclusion　Using Xuanyunning with Sibelium is effective for treatment of vertebrobasilar insufficiency.
　　　【Key words】　Xuanyunning; Sibelium; Vertebrobasilar Insufficiency;Vertigo
　  椎基底动脉供血不足是一种常见的缺血性脑血管病, 是脑血液供应减少的一类疾病, 以眩晕为主, 伴恶心、呕吐、耳聋、耳鸣、肢体麻木, 记忆力减退, 睡眠障碍等症状, 反复发作, 时轻时重, 可有短暂、轻微的神经系统体征, 多伴有高血压或眼底动脉硬化, 该病如不及时治疗, 脑循环障碍可逐渐加重, 甚则发生脑梗死等严重缺血性脑血管病。西比灵是选择性钙离子拮抗剂，是治疗椎基底动脉供血不足性眩晕的常规用药，临床发现西比灵联合桂林三金药业生产的眩晕宁片剂用药治疗效果更佳, 值得推广应用。本文主要比较眩晕宁联合西比灵与单用西比灵治疗椎基底动脉供血不足性眩晕的临床疗效及安全性。
1　临床资料
1.1　一般资料: 本组病人100 例均为我科住院病人, 主要症状符合旋转感、头昏、头痛、恶心、呕吐、耳闷、耳鸣及听力下

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