|
不良妊娠与TORCH感染的关系 |
| |
曹云霞 邱林霞 张庆玲 王红菊 刘华平 陆应玉 肖尚喜
【摘要】 目的 探讨不良妊娠与弓形体(TOX)、其他(OTH)、风疹病毒(RUV)、巨细胞病毒(CMV)、单纯疱疹病毒(HSV-Ⅱ)（TORCH）系列病原体感染的关系。方法 应用酶联免疫吸附试验（ELISA）和聚合酶链反应（PCR）技术，检测54例有不良妊娠史的妇女（试验组）及54例正常孕妇（对照组）母血及胎儿脐血TORCH感染情况。结果 （1）试验组TORCH既往感染率为，CMV 46.29%；RUV 16.29%；TOX 16.67%；HSV-Ⅱ 29.63%。（2）试验组TORCH活动性感染率为，CMV 57.40%；RUV59.26%；TOX 38.89%；HSV-Ⅱ 46.29%。（3）试验组TORCH复发感染率为，CMV 38.89%；RUV38.89%；TOX 11.11%;HSV-Ⅱ 22.22%。以上3个指标，试验组均显著高于对照组(P<0.01)，异常妊娠结局发生率试验组亦显著高于对照组(P<0.01)。试验组TORCH母婴垂直传播率为73.08%。结论 TORCH系列病原体感染是导致妇女不良妊娠结局的重要原因之一，对有不良妊娠史的妇女，行TORCH筛查对防止出生缺陷和围产儿合并症及并发症完全必要，ELISA结合PCR方法是诊断TORCH感染的有效手段。
【关键词】 弓形虫病 风疹 巨细胞病毒感染 妊娠结局 聚合酶链反应
Study on the Relationship between the History of Abnormal Pregnancy and TORCH Infection in Pregnant Woman
CAO Yunxia,QIU Linxia, ZHANG Qingling, et al.
Anhui Medical University, The First Affiliated Hospital, Hefei 230022
【Abstract】 Objective To investigate the relationship between the history of abnormal pregnancy and the Toxoplasma(TOX),Other(OTH),Rubella virus(RUV),Cytomegalo virus(CMV),Herpes simplex virus-Ⅱ(HSV-Ⅱ) (TORCH) infections in pregnant woman. Methods Enzyme-Linked immunosorbent assay(ELISA)combind with polymerase chain reaction (PCR) technique were used to detect TORCH infection in pregnant women with histories of abnormal pregnancies(study group, n=54)and normal pregnant women (control group, n=54).The fetal cord blood samples were also detected. Results In study group,the rates of previous TORCH infection: CMV 46.29%, RUV 16.29%, TOX 16.67%, HSV-Ⅱ 29.63%. The rates of active infection: CMV 57.40%, RUV 59.26%, TOX 38.89%, HSV-Ⅱ 46.29%. The rates of recurrent infection:CMV 38.89%, RUV 38.89%, TOX 11.11%, HSV-Ⅱ 22.22%. These three kinds of infection rates in study group were significantly higher than that of control group (P<0.01). The abnormal pregnant cntcomes in study group were significantly higher than that of control group(P<0.01). The incidence of [1] [2] 下一页
上一个医学论文： 耐甲氧西林金黄色葡萄球菌感染流行的控制和治疗
下一个医学论文： 抑制一氧化氮合成对孕鼠血管调节因子的影响
|
|
|
|
|
|
|
您现在的位置： 绿色健康网 >> 医学论文 >> 妇产科论文 >> 正文