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加压推注溶栓药物治疗急性髂股深静脉血栓形成

作者:韩兴军,田旭东

【关键词】  深静脉;血栓形成;尿激酶;加压;推注
  [摘 要] 目的:探讨髂股深静脉血栓形成(DVT),在顺行造影的同时,加压推注尿激酶的应用。方法:56例DVT,男38例,女18例,右下肢20例,左下肢36例,病程6 h~5 d。从患肢远端浅静脉入路,小腿中下1/3捆扎止血带,使对比剂经深静脉通过,进行下肢深静脉顺行造影的同时,加压间断推注尿激酶,进行溶栓治疗,尿激酶使用20万U~80万U。结果:56例患者均获得了良好的临床疗效,无一例无效,无一例发生症状性肺栓塞,所有患者症状消失或明显减退。结论:经下肢浅静脉加压推注尿激酶进行溶栓治疗髂股DVT,疗效确切,溶解率高,方法简便,安全可靠。
  [关键词] 深静脉;血栓形成;尿激酶;加压;推注
  Add to Press to Push to Note to Dissolve to Bolt a Deep Wein Blood of the Medicine Treatment to Bolt the Formation
  Abstract:Objective To explore deep vein thrombosis and the application of pressures pushes the Urokinase,whichs is suitable direct radiography.Methods 56 examples patients of DVT,male 38 examples,female 18 examples,right lower limb 20 examples,left limb 36 examples,the course of DVT is 6 hours5 days.We push the contrast medicinal form the trouble extremity farend shallow vein,and tie up the tourniquet in the calf next 1/3,enable the contrast medicinal preparation to pass after the deep vein,carries on the lower limb deep vein along good radiography at the same time,pressurize interrupted pushes the Urokinase,carries on dissolves the hitch treatment,the Urokinase uses 20 ten thousand U~80 ten thousand U.Results 56 examples patients have obtained the good clinical curative effect,does not have 1 example to be invalid,does not have 1 example to have the symptom pulmonary embolism,all patients symptom vanishes or obviously drops.Conclusions Pressurizes after the lower limb shallow vein pushes the Urokinase,to carry on dissolves the treatment DVT,the curative effect is accurate,dissolution rate is high,the method is simple,safe is reliable.
  Key words:Deep phlebothrombosis;Thrombosis;Urokinase; Pressuriza; Push
  髂股深静脉血栓形成(Deep Vein Thrombosis.DVT)是静脉系统血栓的好发部位,发病比较隐匿,在日常工作中经常见到,如果得不到及时有效的治疗,将引起肢体血液回流障碍。其发生机制与多种因素有关,但血管壁损伤,血流缓慢,血流高凝状态为其形成的三大要素。现将自2000年以来,我们对56例髂股深静脉血栓形成患者,在顺行加压推注对比剂进行造影的同时,加压推注尿激酶,取得了良好的治疗效果,总结报道如下。
  1 材料和方法
  1.1 病例资料                 
  56例患者男38例,女18例,年龄28岁~73岁

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