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碘染色诊断食管粘膜病变的临床研究 |
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刘宾 龚宝丽 毕春山 吴心洁
摘 要：利用2%复方碘溶液(卢戈氏液)对120例行胃镜检查的患者进行了食管粘膜碘染色。其中100例为肉眼观察可疑粘膜病变者，20例为食管癌术前病例。在100例可疑粘膜病变中，对碘呈不规则染色者82例。经病理检查：早癌2例(经手术证实)，不同程度的不典型增生20例，不同程度炎症53例，7例经病理检查未发现显著病变，病变检出率为91%(75/82)。对20例食管癌患者术前胃镜下碘染对病变范围进行墨汁标记，术后残端癌发生率为0。
关键词：胃镜 卢戈氏液 食管
Clinical study on pathological changes of the esophagued
mucosa by iodine dyeing diagnosis
Liu Bin
(The Beijing Tongren Hospital, Beijing 100730)
Gong Baoli
(The Beijing Tongren Hospital, Beijing 100730)
Bi Chunshan
(The Beijing Tongren Hospital, Beijing 100730)
Abstract：120 patients been received the routine gastroscope examinations, were examined by the iodine dyeing on their esophagus mucosa with 2% compound iodine solution. 100 cases of those patients were suspectably to have abnormal mucosa pathological changes. Through naked-eye inspection, 20 of those were diagnosed as esophageal cancer, preoperatively. Among the 100 cases mentioned above, 82 cases of them were found to have irregularly iodine dyed esophageal mucosa, the following results obtained through the pathological examinations revealed: 2 cases suffered from with early stage of cancers in the initial stage (confirmed by operations); 20 cases with atypical dysplasia in different stages; 53 cases suffered from inflammation in different degrees; no obvious pathological changes 7 cases. The rate of the pathological changes found is 91% (75/82). For the 20 patients suffered from esophageal cancers were iodine dyed under the gastroscopy with the ink marks before operations. No cancer was found post-operativelly.
Key words：Gastroscope Compound iodine solution Esophagus▲
如何提高内镜下对食管病变的检出率，尤其是对早期食管癌的检出，是食管癌防治的关键，也是临床内镜的重要课题。我们报告了内镜下利用卢戈氏液对肉眼难于观察的食管粘膜病变进行诊断及食管癌术前病变范围标记的研究，取得了良好的成绩，显示了色素内镜的实用性。
资料与方法
一、临床资料
全部病例为北京同仁医院1995年～1998年进行胃镜检查的部分门诊及住院病人共120例，其中临床明确诊断食管癌的术前病例20例，内镜下肉眼观察困难的可疑食管粘膜病变的病例100例。使用Olympus XQ-200电子胃[1] [2] 下一页
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