【摘要】目的：观察依沙吖啶羊膜腔内注射配伍米非司酮口服用于剖宫产术后疤痕子宫引产的临床效果。方法：将200例中期妊娠要求引产的疤痕子宫妇女分为观察组(100例)与对照组(100例)，观察组在依沙吖啶羊膜腔内注射引产当日口服米非司酮150mg;对照组常规进行依沙吖啶羊膜腔内注射引产。结果：观察组与对照组引产成功率、产后出血量，比较差异无统计学意义(P>0.05);引产时间、胎盘、胎膜残留情况，胎盘粘连发生率，差异有统计学意义(P<0.05)。结论：依沙吖啶联合米非司酮用于疤痕子宫引产可明显缩短引产时间，减少并发症的发生，是一种理想、安全、有效的引产方法。
【关键词】 米非司酮;依沙吖啶;中期妊娠;疤痕子宫;引产
Clinic effect of combination of ethacridine and mifepristone on induced labor for pregnancy with cicatricial uterine due to caesarean section
GU Yinggan
(Family Planning Guide Station in Jianhu County Jianhu 224700, China)
[ABSTRACT] Objective: To observe the effect of amniotic cavity injection with ethacridine and oral administration of mifepristoneon on induced labor for pregnancy with cicatricial uterine due to caesarean section. Methods： Randomly divided 200 second trimester pregnancy women with cicatricial uterine into observation group (100 cases) and control group (100 cases). Treated observation group with amniotic cavity injection of ethacridine and oral administration of 150 mg mifepristoneon, while treated control group with only ethacridine injection. Results: There was no significantly difference in success rate of induced labor, postpartum bleeding volumn between two groups(P>0.05),while the delivering time,residue status of placenta and fetus membrane in observation group significantly differed from control group(P<0.05). Conclusion: Combined application of ethacridine and mifepristone can markedly shorten delivery time, reduce the occurrence of complication. It is safe and effective.
[KEY WORDS] Ethacridine; Mifepristone; Second trimester pregnancy; Cicatricial uterine; Induced labor
中期妊娠宫颈不成熟，对缩宫素不敏感，依沙吖啶药物本身又无促进宫颈成熟的作用，所以宫颈扩张相对缓慢[1]，剖宫产术后疤痕子宫意外妊娠引产有一定的风险，我院2006年1月～2009年10月对剖宫产术后疤痕子宫的中期妊娠患者使用依沙吖啶联合米非司酮进行引产术，取得了良好的效果，现报道如下。
1 资料与方法
1.1 一般资料
选取2006年1月～2009年10月来站就诊要求终止妊娠的疤痕子宫妇女200例，妊娠16～26周，经血、尿、白带常规，凝血功能及肝功能检查正常，无严重产科及内科并发症和
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