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锥状点式接触钢板内固定对局部皮质骨微循环影响的实验研究 |
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吴雪晖 李起鸿 杨柳 陈锡秋
【摘要】目的研究新型锥状点式接触钢板对局部皮质骨微循环的影响。方法山羊24只，其中4只为正常对照，余20只双侧胫骨中段横行截骨后分别行锥状点式接触钢板和传统钢板固定。术后3d，2、4、9、13周处死动物。用墨汁灌注血管面积图像分析法和放射性微球局部血流量测定法评价钢板下和钢板对侧皮质骨血流量。结果传统钢板板下皮质骨持续缺血，而锥状点式接触钢板板下皮质骨血流量，除术后3d外，其余各时相点均明显高于传统钢板组，术后4周时血流量最高(11.22±0.552)ml/(min．100g)，为正常对照组(3.42±0.728)ml/(min．100g)的3倍多,为传统钢板组(1.13±0.071)ml/(min·100g)的9倍多。而钢板对侧皮质骨缺血只是暂时的，术后2周即已恢复。结论锥状点式接触钢板能保护钢板下皮质骨血循环，更有利于骨折愈合。
【关键词】骨折；内固定器；血管造影术；微循环
An experimental study of the conical cylinder point contact plate on cortical microcirculation
WU Xuehui, LI Qihong, YANG Liu, et al.
（Department of Orthopaedics, Southwest Hospital, The Third Military Medical University, Chongqing 400038， China）
【 Abstract】 Objective To study the influence of conical cylinder point contact (CCPC) plate on cortical microcirculation. Methods 24 adult goats were used in this experiment. 4 of them were used as normal controls. After the transverse osteotomy of middle shaft of both tibiae was operated on 20 goats, fixation with the CCPC－ plate was done in the right tibiae and the conventional plate (CP) in the left. All these animals were sacrificed respectively at 3 days, 2 weeks, 4 weeks, 9 weeks and 13 weeks after surgery. The changes of the cortical microcirculation and hemodynamics beneath and opposite these two plates were evaluated by image analysis of the vessels after the Chinese ink perfusion and radioactive microsphere measurement of regional blood flow. Results The experiment showed that the cortical blood flow volume beneath both plates reduced obviously at the early stage after operation. The cortical blood flow volume beneath the conventional plates was still lower than the normal control even at 13 weeks after operation. The cortical microcirculation beneath the CCPC－ plate was apparently better than that beneath the conventional ones. The blood flow volume reached the highest (11.22± 0.552) ml/(min· [1] [2] 下一页
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