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减肥手术带来意外效果 能降低女性癌症发病率



Weight-losssurgerymayhelpobesewomenlowertheirriskofdevelopingcancer,SwedishresearcherssaidonTuesday.

Theyfoundwomenwhohadweight-losssurgerywere42percentlesslikelytodevelopcancerduringa10-yearstudypublishedinthejournalLancetOncology.

Meninthestudydidnotbenefit,possiblybecausemanycancersaredrivenbyfemalehormonessuchasestrogen,theysaid,orsimplybecausefewermengetweight-losssurgery.

Obesityhaslongbeenknowntoraisetheriskofcancer,andtheevidencecontinuestomount.

AstudyreleasedonTuesdayintheJournaloftheAmericanMedicalAssociationfoundpeoplewhowereobeseasyoungadultshadtwicetheriskofdevelopingpancreaticcancer,anespeciallyaggressivekind.

Weight-lossoperations--inwhichdoctorschangethedigestivesystem'sanatomytocutthevolumeoffoodapersoncaneat--havebeenshowntoreversediabetesandreducetherisksofdyingfromheartdisease.

TheSwedishstudy,ledbyLarsSjostromofSahlgrenskaUniversityHospitalinGothenburg,compared2,010obesepatientswhohadweight-losssurgerywith2,037obesepatientswhogotstandarddietandexercisetreatment.

Overall,theyfoundthesurgeryhelpedpeoplemaintainanaverageweightlossof19.9kgorabout43poundsover10years.Peopleinthedietandexercisegroupgainedanaverageof1.3kgornearly3poundsduringthestudyperiod.

Thesurgerycuttheratesofcancerbyathird,butwomenenjoyedmostofthatbenefit.Amongwomen,therewere79first-timecancersinthesurgerygroup,and130amongthosewhogotstandardtreatment.

Dr.AndrewRenehanoftheUniversityofManchesterintheUnitedKingdomsaidinacommentarytheabsenceofabenefitinmencouldsimplyreflectthenumberofmenwhowereinthestudy.

Hesaidforwomen,thegreatestcancerpreventioneffectswerelikelytobepost-menopausalbreastandendometrialcancers--cancerssensitivetohormonelevels.

Renehansaidtheeffectsofweight-losssurgerymaytakelongertoshowupinmen,whoaremorepronetocolon,rectalandkidneycancers,whichtakelongertobecomeapparent.

Dr.

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