活跃期人工破膜加间苯三酚静推100例临床分析

【摘要】  目的 观察活跃期人工破膜加静推间苯三酚对产程进展的影响。方法 选择正常初产妇300例，随机分成三组：A组100例于活跃期早期人工破膜；B组100例于活跃期早期人工破膜加间苯三酚静推；C组100例未做干预。观察三组的产程变化及母儿情况。结果 三组的总产程差异有显著性；活跃期人工破膜可加速产程进展（P＜0.05）；活跃期人工破膜加静推间苯三酚可更加有效地加速产程进展（P＜0.01）。三组产后出血和新生儿Apgar评分差异无显著性。结论 活跃期人工破膜加静推间苯三酚可有效加速产程进展，且对母儿无明显不良影响。

【关键词】  活跃期；人工破膜；间苯三酚；产程

　　Abstract:Objective To observe the effects of intravenous injection with phloroglucinol plus artificial rupture of fetal membranes on stages of labor. Methods 300 normal primiparas were randomly divided into three groups. Group A was given artificial rupture of fetal membranes in early active phase. Group B was intravenously injected with phloroglucinol at 80 mg after artificial rupture of fetal membranes. And group C was not intervened. The labor time, fetal distress, and postpartum hemorrhage were observed. Results There were significant differences among three groups in total stages of labor. And there was not significantly different in Apgar score in neonates and postpartum hemorrhage among three groups. Conclusion Phloroglucinol plus artificial rupture of fetal membranes in active phase can effectively improve stages of labor, and it is well tolerated by both mother and newborn.

　　Key words:active phase； artificial rupture of fetal membranes； phloroglucinol； stages of labor

　　随着剖宫产率的提高，在分娩过程中适时干预和恰当处理，可以缩短产程，减轻产妇的痛苦，降低母婴并发症,提高阴道分娩率，从而降低剖宫产率，提高产科质量。人工破膜有利于胎先露对宫颈直接压迫，引起反射性子宫收缩力加强；间苯三酚是一种非阿托品罂粟碱类的纯平滑肌解痉药，只作用于痉挛的平滑肌，可加速宫颈扩张作用，人工破膜加静脉用间苯三酚，可协同作用，更加有效加速产程进展。我院对产妇在活跃期人工破膜加静推间苯三酚，可明显缩短产程且对母儿无不良影响，现报道如下。

　　1  资料与方法

　　1.1  临床资料
   
　　选择2004年10月至2007年10月在我院住院分娩无并发症的正常足月单胎初产妇300例，年龄20～35岁，孕周37～41周，排除头盆不称，临产前胎监评分无应激试验（NST）有反应，并具有阴道分娩条件的孕妇，随机分成3组：A组100例，于活跃期早期人工破膜；B组100例，于活跃期早期人工破膜加间苯三酚静推；C组100例未做干预。观察3组的产程变化及母儿情况。各组

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