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异丙酚 安氟醚及其复合组对麻醉后期恢复的影响

范志毅 张兰霞 涂恩平 王庚 谢文钦

摘 要:目的 采用双盲法观察不同麻醉维持方法麻醉后期的恢复情况。方法 30例择期手术的病人,ASA Ⅰ~Ⅱ级,随机分为三组:安氟醚组、异丙酚组及复合组,每组10例。安氟醚组以1%~2%安氟醚吸入维持麻醉,异丙酚组以注射泵经静脉持续输注异丙酚6~12mg.kg-1/h维持麻醉,复合组吸入1%安氟醚并静脉输注异丙酚6~9mg.kg-1/h。结果 安氟醚组的术后呼吸、吞咽反射、呼之睁眼恢复时间明显短于其它二组(P<0.05或P<0.01);术后拔管时间复合组明显长于其它二组(P<0.01);呼吸道梗阻的发生率三组相同;停药-定向力恢复时间三组相同,但拔管-定向力恢复时间复合组明显高于其它二组(P<0.05)。结论 从术后恢复角度看,安氟醚与静脉异丙酚复合维持麻醉是不合理的。
关键词:安氟醚 异丙酚 手术后恢复

The effect of propofol, enflurane and their combination on the postoperative recovery

Fan Zhiyi
(Dept. Anesthesiology, First Hospital of Beijing Medical University, Beijing 100034)
Zhang Lanxia
(Dept. Anesthesiology, First Hospital of Beijing Medical University, Beijing 100034)
Tu Enping
(Dept. Anesthesiology, First Hospital of Beijing Medical University, Beijing 100034)

Abstract:Objective Observing the postoperative recovery for maintenance of anesthesia with double blind method.Methods 30 patients (ASA Ⅰ~Ⅱ) with selective operation allocated randomly into three groups: enflurane group, propofol group and combinative group. Every group had 10 patients. In the enflurane group anesthesia was maintained with 1%~2% enflurane, in the propofol group it was with continuous intravenous infusion of propofol 6~12 mg/kg and in the combinative group it was maintained with both agents.Results  The recovery time of spontaneous breathing, swallowing and opening the eyes by prompting were longer in both propofol and combinative groups than in enflurane group (P<0.05 or P<0.01). Extubation was delayed in the combinative group (P<0.05). The occurrency of restlessness after extubation was higher in the combinative group than the other two groups (P<0.01). The occurency of airway, obstruction, the interval between withdrawing the anesthetics and recovery of orientation was the same in all groups, but the interval between extubation to recovery of orientation was longer in the combinative group than other two groups

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