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新生儿红臀与局部霉菌感染关系的临床观察 |
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严艺 周广玲 赵美玲 杜振玲
摘要 为了解新生儿红臀与霉菌感染的关系，对30例红臀患儿进行前瞻性研究。取红臀患儿患处皮肤脱屑及分泌物涂片检查，霉菌检出阳性率为73.3%(22/30)，其中使用抗生素3天以上的霉菌阳性率为85.0%(17/20)。使用抗生素3天以内或未使用抗生素的霉菌检出率50.0%为(5/10)。霉菌阳性者用自配的制霉菌素药膏局部应用12～24h见效，全部在3天内治愈。提出新生儿红臀特别是长期应用抗生素发生红臀的患儿，发生红臀与霉菌感染有关，应用制霉菌素药膏治疗效果满意。
关键词 新生儿红臀 霉菌感染 制霉菌素
Clinical Observation of the Relationship between Diaper Dermatitis in Newborn and Fungus Infection
Yan Yi,Zhou Guang-ling,Zhao Mei-ling,et al
The Department of Pediatrics of The Fourth Hospital of Xu Zhou,Jiang Su Province,221009.
Abstract To investigate the relationship between diaper dermatitis of newborn and fungus infection,30 newborn with diaper dermatitis were studied.Specimens of desquamations and secretions in affected area were taken with swabs for smear and microscopic examination.The results showed that fungus was found in 22 of 30 cases with a positive rate of 73.3%.The positive rate was 85.0%(17/20) in patients who received antibiotics more than three days.In patients who received antibiotics less than three days or no antibiotics the positive rate was 50.0%(5/10).The local application of self-prepared mycostatin ointment showed effectiveness in 12～24 hours in fungus-positive patients,and were all cured within 3 days.It was concluded that the development of the diaper dermatitis of newborn especially who received antibiotics was related to fungus infection.The self-prepared mycostatin ointment was effective for this disease.
Key words Diaper dermatitis of newborn Fungus infection Mycostatin
新生儿红臀是新生儿期的常见病、多发病，也是新生儿室最常见的护理棘手问题。长期以来，认为新生儿红臀与更换尿布不及时、局部长时间受潮湿刺激、尿布洗涤不当、尿布pH值偏高有关，俗称“尿布疹”。但确切原因并不清楚，所以治疗效果差。皮肤霉菌感染好发于新生儿，其皮损特征与新生儿红臀相似。［1］有报告指出用制霉菌素治疗新生儿红臀有效，［2］说明新生儿红臀可能与霉菌感染有关。为了解新生儿红臀与霉菌感染的关系，为防治该病提供依据，自1996年8月至1998年4月对30例新生儿红臀患儿进行了观察研究，现报告如下。
1 临床资料
新生儿红臀30例，男17例，女13例，年龄均小于1个月，以新生儿肺炎、败血症、新生儿硬肿症、高胆红素血症入院。院外发生的红臀18例，院内发生的12例；30例中应用抗生素治疗原发病3天以上者20例。
2 方 法
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