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小儿慢性胃炎锝标记固体餐胃排空检测 |
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江逊 王茂贵 周润锁 徐海峰 王宝西 方雪娟 曹新建 高峰
【摘要】 目的 通过锝化合物标记的固体餐检测胃排空，了解慢性胃炎及幽门螺杆菌(Hp)感染患儿的胃排空情况。方法 将30例慢性胃炎患儿按悉尼分类法分为轻度、中度、重度慢性胃炎三组；按病理检查结果分为Hp阳性和阴性两组。采用锝化合物标记鸡肝为试餐，对各组患儿进行核素检测分析。结果 轻度慢性胃炎患儿的胃半排空时间(GET1/2)为54.80 min，95%可信区间(95%CI)为 37.49～80.22 min；中度者GET1/2为91.22 min，95%CI为 71.88～119.49 min；重度者GET1/2大于120 min。Hp感染阳性的慢性胃炎患儿的GET1/2大于120 min，Hp感染阴性的慢性胃炎患儿的GET1/2为61.46 min，95%CI为 52.70～73.92 min。结论 慢性胃炎患儿的固体餐GET1/2延缓并随病情加重而延长，不同程度病变间有显著差异；慢性胃炎患儿是否感染Hp其GET1/2有显著差异，Hp感染阳性慢性胃炎患儿的GET1/2明显延迟。
【关键词】 胃炎； 儿童； 锝化合物； 胃排空； 螺杆菌，幽门
Measurements of gastric emptying with technetium -labeled solid meal in children with chronic gastritis
JIANG Xun, WANG Maogui， ZHOU Runsuo
（Department of Pediatrics, Tangdu Hospital, The Fourth Military Medical University, Xi′an 710038, China）
【Abstract】 Objective To investigate the status of gastric emptying in children with chronic gastritis and Helicobacter pylori (Hp) infection. Methods Thirty children with chronic gastritis confirmed by biopsy pathology were classified into mild，moderate and severe groups and in Hp-positive and negative groups, each child was tested by single photon emission computed tomography (SPECT) imaging with a technetium compound (99mTcO-4)-labeled chicken liver solid food and the characteristics of gastric emptying were analyzed. Results The half gastric emptying time (GET1/2) in mild,moderate and severe chronic gastritis groups was 54.80 min, 91.22 min and >120 min，respectively, the 95% confidence interval (95%CI) of mild and moderate chronic gastritis groups was 37.49 - 80.22 min and 71.88 - 119.49 min, respectively. GET1/2 surpassed 120 min in Hp-positive group, but was 61.46 min in Hp negative group, 95%CI was 52.70 - 73.92 min. Conclusion The results indicated that GET1/2 of children with chronic gastritis was prolonged with pathological severity; significant difference was found among mild, moderate and severe groups. GET1/2 in chronic gast[1] [2] 下一页
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